As filed with the Securities and Exchange Commission on March 10, 2020
Registration No. 333-
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM S-8
REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933
Bicycle Therapeutics plc
(Exact name of registrant as specified in its charter)
England and Wales | Not applicable | |
(State or other jurisdiction of incorporation or organization) |
(I.R.S. Employer Identification No.) | |
B900, Babraham Research Campus Cambridge CB22 3AT United Kingdom |
Not applicable | |
(Address of Principal Executive Offices) | (Zip Code) |
Bicycle Therapeutics plc 2019 Share Option Plan, as amended
(Full title of the plan)
Lee Kalowski
Chief Financial Officer
Bicycle Therapeutics Inc.
4 Hartwell Place
Lexington, Massachusetts 02421
(Name and address of agent for service)
(617)945-8155
(Telephone number, including area code, of agent for service)
Copy to:
Laura Berezin
Ryan Sansom
Jaime Chase
Cooley LLP
3175 Hanover Street
Palo Alto, California 94304-1130
Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company” and “emerging growth company” in Rule 12b-2 of the Exchange Act.
Large accelerated filer | ¨ | Accelerated filer | ¨ |
Non-accelerated filer | x | Smaller reporting company | x |
Emerging growth company | x |
If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. x
CALCULATION OF REGISTRATION FEE
Title of securities to be |
Amount to be registered (2) |
Proposed per share (3) |
Proposed maximum aggregate offering price (3) |
Amount of registration fee | ||||
Ordinary shares, nominal value £0.01 per share | 719,748 shares | $14.66 | $10,551,505.68 | $1,369.59 |
(1) | These shares may be represented by the American Depositary Shares (“ADSs”) of Bicycle Therapeutics plc (the “Registrant”). Each ADS represents one Ordinary Share. ADSs issuable upon deposit of the Ordinary Shares registered hereby were registered pursuant to a separate Registration Statement on Form F-6 (File No. 333-231422). |
(2) | The Registrant is filing this Registration Statement to register 719,748 ordinary shares, nominal value £0.01 per share (the “Ordinary Shares”), of the Registrant that became available for issuance under the Bicycle Therapeutics plc 2019 Share Option Plan, as amended (the “Plan”), effective as of January 1, 2020, pursuant to the evergreen increase provision of the Plan. Pursuant to Rule 416 under the Securities Act of 1933, as amended (the “Securities Act”), this Registration Statement shall also cover any additional Ordinary Shares of the Registrant which become issuable under the above-named plan by reason of any stock dividend, stock split, recapitalization or any other similar transaction effected without the receipt of consideration which results in an increase in the number of the Registrant’s outstanding Ordinary Shares. |
(3) | Estimated pursuant to Rule 457(c) and Rule 457(h) solely for the purpose of calculating the registration fee. The proposed maximum offering price per share and proposed maximum aggregate offering price are based on the average of the high and low sale prices of the Registrant’s ADSs as reported on The Nasdaq Global Select Market on March 6, 2020. |
REGISTRATION OF ADDITIONAL SHARES
PURSUANT TO GENERAL INSTRUCTION E
Pursuant to General Instruction E of Form S-8, the Registrant is filing this Registration Statement with the Securities and Exchange Commission (the “Commission”) to register an additional 719,748 Ordinary Shares under the Plan, pursuant to the provisions of the Plan providing for an automatic increase in the number of shares reserved and available for issuance under the Plan on January 1, 2020. In accordance with the instructional note to Part I of Form S-8 as promulgated by the Commission, the information specified by Part I of the Form S-8 has been omitted from this Registration Statement.
PART II
INFORMATION REQUIRED IN THE REGISTRATION STATEMENT
Item 3. | Incorporation of Documents by Reference. |
The following documents filed by the Registrant with the Commission are incorporated herein by reference:
(a) | the contents of the Registrant’s Registration Statement on Form S-8 filed with the Commission on May 23, 2019 (File No. 333-231718); |
(b) | the Registrant’s Annual Report on Form 10-K (File No. 001-38916) for the fiscal year ended December 31, 2019, filed with the Commission on March 10, 2020 ; |
(c) | all other reports filed by the Registrant pursuant to Section 13(a) or Section 15(d) of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), since December 31, 2019; and |
All reports and other documents filed by the Registrant after the date hereof pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Exchange Act prior to the filing of a post-effective amendment which indicates that all securities offered hereby have been sold or which deregisters all securities then remaining unsold, shall be deemed to be incorporated by reference herein and to be part hereof from the date of filing of such reports and documents, except for documents or information deemed furnished and not filed in accordance with the rules of the Commission. Any statement contained in a document incorporated or deemed to be incorporated by reference herein shall be deemed to be modified or superseded for purposes of this Registration Statement to the extent that a statement contained herein or in any subsequently filed document that also is deemed to be incorporated by reference herein modifies or supersedes such statement. Any such statement so modified or superseded shall not be deemed, except as so modified or superseded, to constitute a part of this Registration Statement.
Item 8. | Exhibits. |
Pursuant to the requirements of the Securities Act of 1933, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Cambridge, United Kingdom, on March 10, 2020.
BICYCLE THERAPEUTICS PLC | ||
By: | /s/Kevin Lee | |
Kevin Lee, Ph.D., MBA | ||
Chief Executive Officer |
SIGNATURES AND POWER OF ATTORNEY
We, the undersigned officers and directors of Bicycle Therapeutics plc, hereby severally constitute and appoint Kevin Lee and Lee Kalowski, and each of them singly (with full power to each of them to act alone), our true and lawful attorneys-in-fact and agents, with full power of substitution and resubstitution in each of them for him or her and in his or her name, place and stead, and in any and all capacities, to sign any and all amendments (including post-effective amendments) to this Registration Statement on Form S-8 of Bicycle Therapeutics plc and to file the same, with all exhibits thereto and other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorneys-in-fact and agents, and each of them, full power and authority to do and perform each and every act and thing requisite or necessary to be done in and about the premises, as full to all intents and purposes as he or she might or could do in person, hereby ratifying and confirming all that said attorneys-in-fact and agents or any of them or their or his or her substitute or substitutes may lawfully do or cause to be done by virtue hereof.
Pursuant to the requirements of the Securities Act of 1933, this Registration Statement has been signed below by the following persons in the capacities on March 10, 2020.
Name | Title | |
/s/ Kevin Lee | Chief Executive Officer and Director | |
Kevin Lee, Ph.D., MBA | (Principal Executive Officer) | |
/s/ Lee Kalowski | Chief Financial Officer and President | |
Lee Kalowski, MBA | (Principal Financial and Accounting Officer) | |
/s/ Pierre Legault | Chairman of the Board and Director | |
Pierre Legault, MBA, CPA | ||
/s/ Michael Anstey | Director | |
Michael Anstey, DPhil | ||
/s/ Catherine Bingham | Director | |
Catherine Bingham, MBA | ||
/s/ Janice Bourque | Director | |
Janice Bourque, MBA | ||
/s/ Bosun Hau | Director | |
Bosun Hau | ||
/s/ Veronica Jordan | Director | |
Veronica Jordan, Ph.D. | ||
/s/ Richard Kender | Director | |
Richard Kender | ||
/s/ Carolyn Ng | Director | |
Carolyn Ng, Ph.D. | ||
/s/ Gregory Winter | Director | |
Sir Gregory Winter, FRS | ||
/s/ Lee Kalowski | Authorized Representative in the United States | |
Lee Kalowski, MBA |
Exhibit 5.1
Claire Keast-Butler
+44 (0) 20 7556 4211
ckeastbutler@cooley.com
Bicycle Therapeutics plc
Building 900, Babraham Research Campus
Babraham, Cambridgeshire, CB22 3AT
United Kingdom
10 March 2020
Ladies and Gentlemen:
Re: | Bicycle Therapeutics plc – Registration Statement on Form S-8 – Exhibit 5.1 |
1. | INTRODUCTION |
1.1 | We have acted as English legal advisers to Bicycle Therapeutics plc, a public limited company incorporated in England and Wales (the “Company”), in relation to the preparation and filing of the registration statement on Form S-8 to which this opinion letter is attached as an exhibit (such registration statement, as amended, including the documents incorporated by reference therein, the “Registration Statement”) filed with the United States Securities and Exchange Commission (the “SEC”) pursuant to the United States Securities Act of 1933, as amended (the “Securities Act”) and the rules and regulations promulgated thereunder. |
1.2 | As set out in the Registration Statement, it is proposed that up to 719,748 ordinary shares of the Company each having a nominal value of £0.01 (the “Shares”) will be allotted and issued upon the exercise or settlement of equity awards granted under the Bicycle Therapeutics plc 2019 Share Option Plan, adopted by the Company’s board of directors (the “Board”) on 9 May 2019 and approved by the Company’s shareholders on 13 May 2019 (the “2019 Share Option Plan”). |
1.3 | We are rendering this letter at the request of the Company in connection with the Registration Statement. We have taken instructions solely from the Company. |
1.4 | Except as otherwise defined in this letter, capitalised terms used have the respective meanings given to them in the Registration Statement (as defined above) and headings are for ease of reference only and shall not affect interpretation. |
1.5 | All references to legislation in this letter are to the legislation of England unless the contrary is indicated, and any reference to any provision of any legislation shall include any amendment, modification, re-enactment or extension thereof, as in force on the date of this letter. |
2. | DOCUMENTS |
For the purpose of issuing this letter, we have reviewed the following documents only:
2.1 | a draft PDF copy of the Registration Statement as at 9 March 2020 to be filed with the SEC on 10 March 2020; |
2.2 | a PDF copy of the 2019 Share Option Plan; |
2.3 | a PDF executed copy of the minutes of the meeting of the Board held on 9 May 2019, at which it was resolved, inter alia, to approve the 2019 Share Option Plan and appoint the compensation committee of the board of directors of the Company (the “Compensation Committee”) as administrators of the 2019 Share Option Plan (the “Board Minutes”); |
Cooley (UK) LLP Dashwood 69 Old Broad Street
London EC2M 1QS, UK
t: +44 (0) 20 7583 4055 f: +44 (0) 20 7785 9355 cooley.com
Cooley (UK) LLP is a limited liability partnership and is registered in England and Wales with registered number OC395270. Our registered office is at the address above. Cooley (UK) LLP is authorised and regulated by the Solicitors Regulation Authority (SRA number 617791). A list of the members of Cooley (UK) LLP and their professional qualifications is open to inspection at its registered office. The word 'partner,' used in relation to Cooley (UK) LLP, refers to a member of Cooley (UK) LLP or an employee or consultant of Cooley (UK) LLP (or any affiliated firm) of equivalent standing.
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2.4 | a PDF executed copy of the written resolutions passed by the shareholders of the Company on 13 May 2019, in which it was resolved, inter alia, to approve the 2019 Share Option Plan and granting authorities to the directors of the Company for the purposes of sections 551 and 570 of the Companies Act 2006, as amended (the “Companies Act”) to allot Shares or grant rights to subscribe for Shares (the “Written Shareholder Resolutions”); |
2.5 | a PDF executed copy of the minutes of the meeting of the Compensation Committee held on 12 September 2019, at which it was resolved, inter alia, to delegate certain authorities of the Compensation Committee to the Chief Executive Officer of the Company to grant certain equity awards (the “Committee Minutes”); |
2.6 | a PDF copy of the certificate of incorporation of the Company dated 27 October 2017 and a PDF copy of the certificate of incorporation on re-registration of the Company as a public company dated 22 May 2019; and |
2.7 | a PDF copy of the current articles of association of the Company adopted on 13 May 2019 (the “Articles”). |
3. | SEARCHES |
In addition to examining the documents referred to in paragraph 2 (Documents), we have carried out the following searches only:
3.1 | an online search at Companies House in England and Wales (“Companies House”) with respect to the Company, carried out at 10:04 a.m. (London time) on 10 March 2020 (the “Online Search”); and |
3.2 | a telephone enquiry at the Companies Court in London of the Central Registry of Winding-up Petitions in England and Wales with respect to the Company, carried out at 10:04 a.m. (London time) on 10 March 2020 (the “Telephone Enquiry” and, together with the Online Search, the “Searches”). |
4. | OPINION |
Subject to the assumptions set out in paragraph 5 (Assumptions), the scope of the opinion set out in paragraph 6 (Scope of Opinion) and the reservations set out in paragraph 7 (Reservations), and subject further to the following:
4.1 | the Registration Statement, as finally amended, having become effective under the Securities Act; |
4.2 | the delegations of authority to the Compensation Committee and the Company’s Chief Executive Officer having been validly effected (among other things, in accordance with article 98 of the Company’s Articles, the 2019 Share Option Plan and applicable laws); |
4.3 | the directors of the Company (the “Directors”), the Compensation Committee or the Company’s Chief Executive Officer having validly granted the awards in respect of the Shares under the 2019 Share Option Plan; |
4.4 | the Directors or the Compensation Committee having validly resolved to allot and issue the Shares, or grant rights to subscribe for the Shares, at duly convened and quorate meetings of the Board or the Compensation Committee, or by way of duly passed written resolutions of the Board or the Compensation Committee in compliance with all applicable laws and regulations and with such resolutions being in full force and effect and not having been rescinded or amended; |
4.5 | the receipt in full of payment for the Shares in an amount of “cash consideration” (as defined in section 583(3) of the Companies Act) of not less than the aggregate nominal value for such Shares, assuming in each case that the individual grants or awards under the 2019 Share Option Plan are duly authorised by all necessary corporate action and duly granted or awarded and exercised in accordance with the requirements of applicable law, the Company’s Articles and the 2019 Share Option Plan (and the agreements and awards duly adopted thereunder and in accordance therewith); and |
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4.6 | valid entries having been made in relation to the allotment and issue of the Shares in the books and registers of the Company, |
it is our opinion that the Shares, if and when allotted and issued, registered in the name of the recipient in the register of members of the Company and delivered in accordance with the terms and conditions referred to in the 2019 Share Option Plan, and as described in the Registration Statement, will be duly and validly authorised and issued, fully paid or credited as fully paid (subject to the receipt of valid consideration by the Company for the issue thereof) and will not be subject to any call for payment of further capital.
5. | ASSUMPTIONS |
In giving the opinion in this letter, we have assumed (without making enquiry or investigation) that:
5.1 | all signatures, stamps and seals on all documents are genuine. All original documents are complete, authentic and up-to-date, and all documents submitted to us as a copy (whether by email or otherwise) are complete and accurate and conform to the original documents of which they are copies and that no amendments (whether oral, in writing or by conduct of the parties) have been made to any of the documents since they were examined by us; |
5.2 | where a document has been examined by us in draft or specimen form, it will be or has been duly executed in the form of that draft or specimen; |
5.3 | the Articles referred to in paragraph 2.7 of this letter remain in full force and effect, and no alteration has been made or will be made to the Articles, in each case prior to the relevant date of the granting of rights to subscribe for the Shares and/or the allotment and issue of the Shares (each such date, an “Allotment Date”); |
5.4 | at the time of each allotment and issue of any Shares the Company shall have received in full “cash consideration” (as such term is defined in section 583(3) of the Companies Act) equal to the subscription price payable for such Shares and shall have entered the holder or holders thereof in the register of members of the Company showing that all such Shares shall have been fully paid up as to their nominal value and any premium thereon as at each Allotment Date; |
5.5 | the 2019 Share Option Plan has been validly adopted and remains in full force and effect, and no alteration has been made or will be made to the 2019 Share Option Plan prior to any Allotment Date; |
5.6 | in relation to any allotment and issue of any Shares by the Company pursuant to the 2019 Share Option Plan, the recipient shall have become entitled to such Shares under the terms of the 2019 Share Option Plan and such Shares will or rights over Shares, where applicable, will be fully vested each in accordance with the terms of the 2019 Share Option Plan and such recipient has or will have complied with all other requirements of the 2019 Share Option Plan in connection with the allotment and issue of such Shares; |
5.7 | all awards have been made under the terms of the 2019 Share Option Plan, that the terms of all awards have not materially deviated from the terms set out in the 2019 Share Option Plan and that any Shares will be allotted and issued in accordance with the terms set out in the 2019 Share Option Plan, in accordance with the Articles and applicable laws; |
5.8 | immediately prior to each Allotment Date, the Directors shall have sufficient authority and powers conferred upon them to allot and issue such Shares and grant such rights (as applicable) under section 551 of the Companies Act and under section 570 of the Companies Act as if section 561 of the Companies Act did not apply to such allotment and issue or grant, and the Directors shall not allot or issue (or purport to allot or issue) Shares and shall not grant rights (or purport to grant rights) to acquire Shares in excess of such powers or in breach of any other limitation on their power to allot and issue Shares or grant rights to acquire Shares; |
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5.9 | no Shares shall be allotted or issued, or are or shall be committed to be allotted or issued, at a discount to their nominal value (whether in dollars or equivalent in any other currency); |
5.10 | all documents, forms and notices which should have been delivered to Companies House in respect of the Company have been so delivered; |
5.11 | the information revealed by the Searches is true, accurate, complete and up-to-date in all respects, and there is no information which should have been disclosed by the Searches that has not been disclosed for any reason and there has been no alteration in the status or condition of the Company since the date and time that the Searches were made and that the results of the Searches will remain complete and accurate as at each Allotment Date; |
5.12 | in relation to the allotment and issue of the Shares, the Directors have acted and will act in the manner required by section 172 of the Companies Act and the Shares will be allotted and issued in good faith and on bona fide commercial terms and on arms’ length terms and for the purpose of carrying on the business of the Company and that there are reasonable grounds for believing that the allotment and issue of the Shares will promote the success of the Company for the benefit of its members as a whole; |
5.13 | there has not been and will not be any bad faith, breach of trust, fraud, coercion, duress or undue influence on the part of any of the Directors in relation to any allotment and issue of Shares; |
5.14 | the Board Minutes and the Committee Minutes referred to in paragraphs 2.3 and 2.5 (Documents), respectively, provided to us in connection with the giving of this opinion, are a true record of the proceedings described therein, and that each meeting recorded in such minutes was and each meeting of the Directors or the Compensation Committee referred to in paragraph 4.4 of this letter were and/or will be duly conducted as described therein, duly constituted and convened and all constitutional, statutory and other formalities were and/or will be duly observed (including, if applicable, those relating to the declaration of Directors’ interests or the power of interested Directors to vote), a quorum was and/or will be present throughout, the requisite majority of Directors voted and/or will vote in favour of approving the resolutions and the resolutions passed at that meeting of the Board or Compensation Committee, as applicable, were and/or will be duly adopted, have not been and will not be revoked or varied and remain in full force and effect and will remain so as at each relevant Allotment Date; |
5.15 | the Written Shareholder Resolutions were duly passed as written resolutions on 13 May 2019, the requisite majority of eligible shareholders have signed one or more copies of the written resolutions, all provisions of the Companies Act and the Articles were duly observed and such resolutions were duly passed and have not been revoked or varied and remain in full force and effect and will remain so as at each Allotment Date, and all filings required to be made with Companies House in connection therewith have been made within the relevant time limits; |
5.16 | as at each Allotment Date, the authorities granted pursuant to the Written Shareholder Resolutions will remain unutilised to the extent necessary to permit such allotment and issue, or if at any Allotment Date such authorities have expired, the Company in general meeting having duly and validly resolved (i) as an ordinary resolution to authorise the Directors pursuant to section 551 of the Companies Act to allot the Shares, or grant rights to subscribe for the Shares, pursuant to the 2019 Share Option Plan and (ii) as a special resolution to empower the Directors pursuant to section 570 of the Companies Act to allot such Shares and grant such rights (as applicable), free of the restrictions in section 561 of the Companies Act; |
5.17 | the resolutions of the shareholders of the Company referred to in paragraph 5.16 will be duly passed as resolutions of the Company, all constitutional, statutory and other formalities will be observed and such resolutions will not have expired and will not be revoked or varied prior to each Allotment Date and will remain in full force and effect as at each Allotment Date; |
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5.18 | the Company has complied and will comply with all applicable anti-terrorism, anti-money laundering, sanctions and human rights laws and regulations and that each grant of rights to acquire Shares under the 2019 Share Option Plan and that each allotment and issue of Shares pursuant to the 2019 Share Option Plan will be consistent with all such laws and regulations; |
5.19 | no Shares or rights to subscribe for Shares have been or shall be offered to the public in the United Kingdom in breach of the Financial Services and Markets Act 2000 (“FSMA”), the EU Prospectus Regulation (Regulation (EU) 2017/1129) or of any other United Kingdom laws or regulations concerning offers of securities to the public, and no communication has been or shall be made in relation to the Shares in breach of section 21 (Restrictions on financial promotion) of FSMA or any other United Kingdom laws or regulations relating to offers or invitations to subscribe for, or to acquire rights to subscribe for or otherwise acquire, shares or other securities; |
5.20 | in issuing and allotting and granting rights to acquire Shares and administering the 2019 Share Option Plan, the Company is not carrying on a regulated activity (within the meaning of section 19 (The general prohibition) of FSMA); and |
5.21 | the Company has not taken any corporate or other action nor have any steps been taken or legal proceedings been started against the Company for the liquidation, winding-up, dissolution, reorganisation or bankruptcy of, or for the appointment of a liquidator, receiver, trustee, administrator, administrative receiver or similar officer of, any such party (including the Company) or all or any of its or their assets (or any analogous proceedings in any jurisdiction) and no such steps or proceedings will have been taken as at each Allotment Date, and the Company is not unable to pay its debts as they fall due within the meaning of section 123 of the Insolvency Act 1986, as amended (the “Insolvency Act”) and will not become unable to pay its debts within the meaning of that section as a result of any of the transactions contemplated herein, is not insolvent and has not been dissolved or declared bankrupt (although the Searches gave no indication that any winding-up, dissolution or administration order or appointment of a receiver, administrator, administrative receiver or similar officer has been made with respect to the Company) and such actions and steps will not have been taken as at any Allotment Date. |
6. | SCOPE OF OPINION |
6.1 | The opinion given in this letter is limited to English law as it would be applied by English courts (including the laws of the European Union to the extent having the force of law in England) on the date of this letter. |
6.2 | We express no opinion in this letter on the laws of any other jurisdiction and, in particular, we express no opinion on the laws of the European Union as it affects any jurisdiction other than England. We have not investigated the laws of any country other than England and we assume that no foreign law (other than the laws of the European Union to the extent having the force of law in England) affects the opinion stated in paragraph 4 (Opinion). |
6.3 | We express no opinion as to any agreement, instrument or other document other than as specified in this letter. For the purposes of giving the opinion in paragraph 4 (Opinion), we have only examined and relied on those documents set out in paragraph 2 (Documents) and made those searches and enquiries set out in paragraph 3 (Searches), respectively. We have made no further enquiries concerning the Company or any other matter in connection with the giving of the opinion in paragraph 4 (Opinion). |
6.4 | No opinion is expressed with respect to taxation in the United Kingdom or otherwise in this letter. |
6.5 | We have not been responsible for investigating or verifying the accuracy of the facts or the reasonableness of any statement of opinion or intention, contained in or relevant to any document referred to in this letter, or that no material facts have been omitted therefrom. |
6.6 | The opinion given in this letter is given on the basis of each of the assumptions set out in paragraph 5 (Assumptions) and is subject to each of the reservations set out in paragraph 7 (Reservations) to this letter. The opinion given in this letter is strictly limited to the matters stated in paragraph 4 (Opinion) and does not extend, and should not be read as extending, by implication or otherwise, to any other matters. |
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6.7 | This letter only applies to those facts and circumstances which exist as at today’s date and we assume no obligation or responsibility to update or supplement this letter to reflect any facts or circumstances which may subsequently come to our attention, any changes in laws which may occur after today, or to inform the addressee of any change in circumstances happening after the date of this letter which would alter the opinion given in this letter. |
6.8 | This letter is given by Cooley (UK) LLP and no partner or employee assumes any personal responsibility for it nor shall owe any duty of care in respect of it. |
6.9 | This letter, the opinion given in it, and any non-contractual obligations arising out of or in connection with this letter and/or the opinion given in it, are governed by and shall be construed in accordance with English law as at the date of this letter. |
7. | RESERVATIONS |
7.1 | The Online Search described at paragraph 3.1 (Searches) is not capable of revealing conclusively whether or not: |
(a) | a winding-up order has been made or a resolution passed for the winding-up of a company; |
(b) | an administration order has been made; or |
(c) | a receiver, administrative receiver, administrator or liquidator has been appointed, |
since notice of these matters may not be filed with the Registrar of Companies in England and Wales immediately and, when filed, may not be entered on the public database or recorded on the public microfiches of the relevant company immediately.
In addition, such a company search is not capable of revealing, prior to the making of the relevant order, whether or not a winding-up petition or a petition for an administration order has been presented.
7.2 | The Telephone Enquiry described at paragraph 3.2 (Searches) relates only to a compulsory winding-up and is not capable of revealing conclusively whether or not a winding-up petition in respect of a compulsory winding-up has been presented, since details of the petition may not have been entered on the records of the Central Registry of Winding-up Petitions in England and Wales immediately or, in the case of a petition presented to a County Court in England and Wales, may not have been notified to the Central Registry of Winding-up Petitions in England and Wales and entered on such records at all, and the response to an enquiry only relates to the period of approximately four years prior to the date when the enquiry was made. We have not made enquiries of any District Registry or County Court in England and Wales. |
7.3 | The opinion set out in this letter is subject to: (i) any limitations arising from applicable laws relating to insolvency, bankruptcy, administration, reorganisation, liquidation, moratoria, schemes or analogous circumstances; and (ii) an English court exercising its discretion under section 426 of the Insolvency Act (co-operation between courts exercising jurisdiction in relation to insolvency) to assist the courts having the corresponding jurisdiction in any part of the United Kingdom or any relevant country or territory. |
7.4 | We express no opinion as to matters of fact. |
7.5 | We have made no enquiries of any individual connected with the Company. |
7.6 | We express no opinion on the compliance of the 2019 Share Option Plan, or the compliance of any award made under the 2019 Share Option Plan, with the rules or regulations of the NASDAQ Global Market or the rules or regulations of any other securities exchange that are applicable to the Company. |
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7.7 | We have not been responsible for investigating or verifying the accuracy of the facts, including statements of foreign law, or the reasonableness of any statements of opinion, contained in the Registration Statement, or that no material facts have been omitted from the Registration Statement. |
7.8 | A certificate, documentation, notification, opinion or the like might be held by the English courts not to be conclusive if it can be shown to have an unreasonable or arbitrary basis or in the event of a manifest error. |
7.9 | We express no opinion in relation to the legality, enforceability or validity of the 2019 Share Option Plan or any award agreement entered into pursuant to such 2019 Share Option Plan. In particular, but without prejudice to the generality of the foregoing, we have assumed that the Shares to be allotted under the 2019 Share Option Plan or any such award agreement will be paid up in full (as to their nominal value and any premium) in cash (within the meaning of section 583(1) of the Companies Act) and we express no opinion as to whether any consideration other than “cash consideration” (as such term is defined in section 583(3) of the Companies Act) which might be paid, or purport to be paid, for the Shares would result in such Shares being validly issued, fully paid and not subject to any call for payment of further capital. |
8. | DISCLOSURE AND RELIANCE |
8.1 | This letter is addressed to you solely for your benefit in connection with the Registration Statement. We consent to the filing of this letter as an exhibit to the Registration Statement. In giving such consent, we do not thereby admit that we are in the category of persons whose consent is required under section 7 of the Securities Act or the rules and regulations promulgated thereunder. |
8.2 | This letter may not be relied upon by you for any other purpose, or furnished to, assigned to, quoted to, or relied upon by any other person, firm or other entity for any purpose, other than for the purpose set out in above in paragraph 8.1, without our prior written consent, which may be granted or withheld at our sole discretion. |
Yours faithfully
/s/ Cooley (UK) LLP |
Cooley (UK) LLP
Exhibit 23.1
CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
We hereby consent to the incorporation by reference in this Registration Statement on Form S-8 of Bicycle Therapeutics plc of our report dated March 10, 2020 relating to the financial statements, which appears in Bicycle Therapeutics plc's Annual Report on Form 10-K for the year ended December 31, 2019.
/s/ PricewaterhouseCoopers LLP | |
Cambridge, United Kingdom | |
March 10, 2020 |